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My thoughts and learning experiences regarding cellular immunology, cytokine assays and biology in general.
Friday, March 12, 2004
Misc notes for myself...
B cells, or B cell lymphocytes: B cells spend their entire early life in the bone marrow. Upon maturity, theytravel throughout the bloodstream and lymph, looking for antigens with which they can interlock. Upon identifying an antigen, a B cell starts replicating itself. These cloned cells mature into antibody-manufacturing plasma cells.
On the other hand T cells, or T cell lymphocytes leave the marrow at any early age, and mature in the thymus. Here they are imprinted with critical information for recognizing “self” and “non-self” substances. Depending on the variety, T cells can kill invading pathogens (killer T cells), or they can detect antigens and secrete cytokines to mobilize other immune system reactions (helper T cells), or they can modulate the immunity response, to prevent it from going out of control (suppressor T cells).
B cells, or B cell lymphocytes: B cells spend their entire early life in the bone marrow. Upon maturity, theytravel throughout the bloodstream and lymph, looking for antigens with which they can interlock. Upon identifying an antigen, a B cell starts replicating itself. These cloned cells mature into antibody-manufacturing plasma cells.
On the other hand T cells, or T cell lymphocytes leave the marrow at any early age, and mature in the thymus. Here they are imprinted with critical information for recognizing “self” and “non-self” substances. Depending on the variety, T cells can kill invading pathogens (killer T cells), or they can detect antigens and secrete cytokines to mobilize other immune system reactions (helper T cells), or they can modulate the immunity response, to prevent it from going out of control (suppressor T cells).
